Volume : 7, Issue : 11, November - 2018
Clinical Characteristics Of Migraine Headache, Eight years' Experience In Misan Province From 2010 to 2018
Khalid Obaid Mohsin
Abstract :
<p> </p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align: justify;direction:ltr;unicode-bidi:embed"><b><span style="font-size:14.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; mso-bidi-language:AR-IQ">Background:</span></b><b><span style="font-size:14.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; color:#4BACC6;mso-themecolor:accent5;mso-font-width:110%"><o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align: justify;direction:ltr;unicode-bidi:embed"><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; mso-font-width:110%">Migraine<span style="letter-spacing:-.95pt"> </span>is<span style="letter-spacing:-.95pt"> </span>a<span style="letter-spacing:-.9pt"> </span>common<span style="letter-spacing:-.95pt"> primary headache <span style="mso-spacerun:yes"> </span></span><span style="letter-spacing:-.05pt">intermittently</span><span style="letter-spacing:-.95pt"> </span>debilitating<span style="letter-spacing: -1.3pt"> </span><span style="letter-spacing:-.05pt">neuro</span><span style="letter-spacing:-.1pt">vascular</span><span style="letter-spacing:-1.25pt"> </span>disorder<span style="letter-spacing:-1.3pt"> </span>that<span style="letter-spacing:-1.25pt"> </span>affects<span style="letter-spacing:-1.8pt"> </span>younger<span style="letter-spacing:-1.75pt"> </span>adults,<span style="letter-spacing:-1.8pt"> </span>especially<span style="letter-spacing: -1.75pt"> </span>women.</span><span style="font-size:12.0pt;line-height:115%; font-family:"Times New Roman","serif";mso-ascii-theme-font:major-bidi; mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi;mso-font-width: 109%"> </span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;mso-font-width:110%">The<span style="letter-spacing:-1.9pt"> </span>diagnosis<span style="letter-spacing:-1.9pt"> </span>is<span style="letter-spacing:-1.85pt"> </span>generally<span style="letter-spacing:-1.9pt"> </span>made<span style="letter-spacing:-1.85pt"> </span>based</span><span style="font-size:12.0pt;line-height:115%;font-family: "Times New Roman","serif";mso-ascii-theme-font:major-bidi;mso-hansi-theme-font: major-bidi;mso-bidi-theme-font:major-bidi;mso-font-width:104%"> </span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;mso-font-width:110%">on<span style="letter-spacing:-.9pt"> </span>clinical<span style="letter-spacing:-.85pt"> </span>criteria,<span style="letter-spacing: -.9pt"> </span>with<span style="letter-spacing:-.85pt"> </span>neuroimaging used<span style="letter-spacing:-1.95pt"> </span>in<span style="letter-spacing: -1.9pt"> </span>some<span style="letter-spacing:-1.9pt"> </span>cases<span style="letter-spacing:-1.95pt"> </span>to<span style="letter-spacing:-1.9pt"> </span>exclude<span style="letter-spacing:-1.9pt"> </span>second</span><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; mso-font-width:105%">ary<span style="letter-spacing:-.8pt"> </span>causes<span style="letter-spacing:-.8pt"> </span>of<span style="letter-spacing:-.8pt"> </span><span style="letter-spacing:-.05pt">headache.</span></span><b><span lang="AR-SA" dir="RTL" style="font-size:14.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;color:#4BACC6;mso-themecolor:accent5;mso-font-width:110%"><o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align: justify;direction:ltr;unicode-bidi:embed"><b><span style="font-size:14.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; mso-bidi-language:AR-IQ">Objectives:</span></b><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; mso-bidi-language:AR-IQ"> This study conducted to highlights the followings clinical <span style="mso-spacerun:yes"> </span>observations about migraine in out-patients sample<span style="mso-spacerun:yes"> </span>in Misan province , Iraq .The types and subtypes of migraine , prevalence <span style="mso-spacerun:yes"> </span>duration and frequency of acute attacks <span style="mso-spacerun:yes"> </span>,and severity ,disability –quality of life affection and complications. <span style="mso-spacerun:yes"> </span></span><b><span lang="AR-IQ" dir="RTL" style="font-size:14.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;mso-bidi-language:AR-IQ"><o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align: justify;direction:ltr;unicode-bidi:embed"><b><span style="font-size:14.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; mso-bidi-language:AR-IQ">Patients and methods: </span></b><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-fareast-font-family:"Times New Roman"; mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi">Out-patients based cohort prospective study , was conducted<span style="mso-spacerun:yes"> </span></span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;color:#252525">in<span style="letter-spacing:1.8pt"> </span><span style="letter-spacing:-.05pt">Misan</span><span style="letter-spacing:1.85pt"> </span>province<span style="letter-spacing:1.85pt"><span style="mso-spacerun:yes"> </span>over nine years </span><span style="letter-spacing:-.05pt">from</span><span style="letter-spacing:1.7pt"> </span><span style="letter-spacing:-.05pt">January</span><span style="letter-spacing:1.7pt"> </span>2010<span style="letter-spacing:1.85pt"> </span>to<span style="letter-spacing:1.85pt"> </span>July<span style="letter-spacing:1.7pt"> </span><span style="letter-spacing:-.05pt">2018.</span></span><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-fareast-font-family:"Times New Roman";mso-hansi-theme-font:major-bidi; mso-bidi-theme-font:major-bidi"> The<span style="mso-spacerun:yes"> </span>total number of the sample was 1412 patients .aged<span style="mso-spacerun:yes"> </span>12 to < 50 years old,<span style="mso-spacerun:yes"> </span>both gender .with a diagnosis of<span style="mso-spacerun:yes"> </span>migraine headache<span style="mso-spacerun:yes"> </span>according to the criteria of<span style="mso-spacerun:yes"> </span>International Classification of Headache Disorders (ICHD-III b version) <span style="mso-spacerun:yes"> </span>.</span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi"> Slandered <span style="letter-spacing:-.05pt"><span style="mso-spacerun:yes"> </span>descriptive</span><span style="letter-spacing: -.1pt"> </span><span style="letter-spacing:-.05pt">statistics </span><span style="letter-spacing:-.1pt">analysis had been used.</span></span><b><span style="font-size:14.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;mso-bidi-language:AR-IQ"><o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align: justify;direction:ltr;unicode-bidi:embed"><b><span style="font-size:14.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; color:#252525;letter-spacing:-.05pt">Results : </span></b><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;color:#252525;letter-spacing:-.05pt">Total number of sample was 1412 patient with migraine head ache , female were 1100, [77.9%], male were 312 [22.1%], female/male ratio 3.5:1 (CI 95%<i> p</i>=0.05).</span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;letter-spacing:-.05pt;mso-bidi-language:AR-IQ"> Median<span style="mso-spacerun:yes"> </span>age ±SD Years ( 21±5.42) years .range (12-45 )years .and ,Mean age / years<span style="mso-spacerun:yes"> </span>at which the first attack was ( 17±4.91) year .</span><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; letter-spacing:-.05pt"><span style="mso-spacerun:yes"> </span>The<span style="mso-spacerun:yes"> </span>prevalence rate<span style="mso-spacerun:yes"> </span>percentage [%]<span style="mso-spacerun:yes"> </span></span><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; color:#231F20">Migraine without aura was the commonest [68 %],the second most common was migraine with aura [9 %].while chronic migraine with continuous pain is the third most common type of migraine,[6.4%].The mean frequency of attacks is (</span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;letter-spacing:-.05pt;mso-bidi-language:AR-IQ">2±4.63) day/month. About [48%] of patients experience non-specific prodrome 1-1.5 hours before attacks Collectively about [27%]of patient in this study experienced<span style="mso-spacerun:yes"> </span>aura during the period of stud.</span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;color:#252525;letter-spacing:-.05pt">Severity of migraine headache it<span style="mso-spacerun:yes"> </span>depends on ( frequency , duration of attacks ) ,we added in this study disabling symptoms , systemic hypotension and changes in level of consciousness by Glasgow coma scale . In general the acute attacks were moderate to severe , with mean duration of 24 hours (60%) p < 0.01. with mean frequency days /month about 2 to 4 / month in ( 94%) p <0.05 ,but very few patient (0.5%) the frequency may reach 14 to 16 /month especially in chronic migraine. </span><b><span style="font-size:14.0pt;line-height:115%; font-family:"Times New Roman","serif";mso-ascii-theme-font:major-bidi; mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi;color:#252525; letter-spacing:-.05pt"><o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align: justify;direction:ltr;unicode-bidi:embed"><b><span style="font-size:14.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; color:#252525;letter-spacing:-.05pt">Conclusions:</span></b><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;color:#252525;letter-spacing:-.05pt"> Migraine is<span style="mso-spacerun:yes"> </span>a common<span style="mso-spacerun:yes"> </span>cause of primary headache </span><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-fareast-font-family:Calii;mso-hansi-theme-font:major-bidi; mso-bidi-theme-font:major-bidi;color:#231F20">th<span style="letter-spacing: .05pt">a</span>t<span style="letter-spacing:.35pt"> </span><span style="letter-spacing:.05pt">is</span><span style="letter-spacing:1.7pt; mso-font-width:83%"> </span>responsible<span style="letter-spacing:-.75pt"> </span>for<span style="letter-spacing:-.7pt"> </span>frequent<span style="letter-spacing:-.7pt"> </span>episodes<span style="letter-spacing:-.7pt"> </span>of<span style="letter-spacing:-.7pt"> </span>tem<span style="letter-spacing:.05pt">p</span><span style="letter-spacing:.1pt">orary</span><span style="letter-spacing:-.75pt"> </span>disability<span style="letter-spacing:-.7pt"> </span></span><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; color:#252525;letter-spacing:-.05pt"><span style="mso-spacerun:yes"> </span>.</span><span style="font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-fareast-font-family:"Times New Roman"; mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi;color:#222222">In this study a confirms an increase in risk of stroke among women with migraine who use estrogen containing contraceptives</span><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif";mso-ascii-theme-font: major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font:major-bidi; color:#252525;letter-spacing:-.05pt">. The acute migraine attacks varying in their frequency ,duration of attacks . non-specific prodromal symptoms ,triggering factors between patients attacks<span style="mso-spacerun:yes"> </span>in the same individual.<span style="mso-spacerun:yes"> </span></span><span style="font-size:14.0pt;line-height:115%;font-family:"Times New Roman","serif"; mso-ascii-theme-font:major-bidi;mso-hansi-theme-font:major-bidi;mso-bidi-theme-font: major-bidi;color:#252525;letter-spacing:-.05pt"><o:p></o:p></span></p>
Keywords :
Cite This Article:
Clinical Characteristics Of Migraine Headache, Eight years' Experience In Misan Province From 2010 to 2018 , Khalid Obaid Mohsin , GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-11 | November-2018


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