Volume : 7, Issue : 10, October - 2018

The prevalence of squamous cell carcinoma in different sites of oral cavity at a tertiary referral centre in Hyderabad, Telangana - A retrospective 5-year study

Dr Vaishali Narayen, Dr Ndvn Shyam, Dr G Kiran Kumar, Dr Nishanth Palakurthi

Abstract :

<p class="Default" style="text-align:justify;line-height:200%"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;&#10;mso-bidi-font-family:&quot;Times New Roman&quot;;color:black;mso-themecolor:text1;&#10;mso-ansi-language:EN-US">Background:</span></b><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;&#10;mso-bidi-font-family:&quot;Times New Roman&quot;;color:black;mso-themecolor:text1;&#10;mso-ansi-language:EN-US"> The purpose of this study was to determine the prevalence of Oral squamous cell carcinomas (OSCCs) </span><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;mso-bidi-font-family:&quot;NaomiSans EFN Light&quot;;&#10;mso-ansi-language:EN-US">depending upon the involve&shy;ment of different sites of oral cavity, its variation with age and gender</span><span style="font-family:&#10;&quot;Times&quot;,&quot;serif&quot;;mso-bidi-font-family:&quot;Times New Roman&quot;;color:black;mso-themecolor:&#10;text1;mso-ansi-language:EN-US">over a period of 5 years and to compare withother national and international studies. </span><span style="font-family:&#10;&quot;NaomiSans EFN Light&quot;,&quot;sans-serif&quot;;mso-fareast-font-family:Calii;mso-fareast-theme-font:&#10;minor-latin;mso-bidi-font-family:&quot;NaomiSans EFN Light&quot;;mso-ansi-language:EN-US"><o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;mso-layout-grid-align:&#10;none;text-autospace:none"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;color:black;mso-themecolor:text1;mso-ansi-language:&#10;EN-US">Materials and Methods:</span></b><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;&#10;color:black;mso-themecolor:text1;mso-ansi-language:EN-US"> Data for the study were obtained from the reports of patients diagnosed with OSCCs between </span><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;mso-bidi-font-family:&quot;&Uuml;]&iuml;&Ntilde;˛&quot;;color:black;&#10;mso-themecolor:text1;mso-ansi-language:EN-US">2014 and 2018 </span><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;color:black;mso-themecolor:text1;mso-ansi-language:&#10;EN-US">and the following variables were analyzed: age, gender and anatomical location.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;tab-stops:81.15pt"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-family:&quot;Times&quot;,&quot;serif&quot;">Statistical Analysis:</span></b><span lang="EN-IN" style="font-family:&quot;Times&quot;,&quot;serif&quot;">The data was analysed with Statistical Package for Social Sciences (SPSS) for Windows 20.0 (SPSS, Inc. Chicago, Illinois). The observed data was analyzed by Pearson&rsquo;s Chi square test. Confidence intervals were set at 95% and values of p &lt; 0.05 were interpreted as statistically significant.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;mso-layout-grid-align:&#10;none;text-autospace:none"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;color:black;mso-themecolor:text1;mso-ansi-language:&#10;EN-US">Results:</span></b><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;color:black;&#10;mso-themecolor:text1;mso-ansi-language:EN-US"> In a total of 1620 biopsies, OSCCs accounted for 364among all the lesions. Maximum number of cases fell in the age group of 40-59 years among which 170 were male. The most common site was buccal mucosa followed by lateral border of the tongue.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;mso-layout-grid-align:&#10;none;text-autospace:none"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;color:black;mso-themecolor:text1;mso-ansi-language:&#10;EN-US">Conclusion:</span></b><span style="font-family:&quot;Times&quot;,&quot;serif&quot;;&#10;color:black;mso-themecolor:text1;mso-ansi-language:EN-US"> This study provides epidemiological information on OSCCs at an institutional level. The relative frequency of these OSCCs can be analyzed at a global level to understand their prevalence, incidence biological behavior, and distribution.<o:p></o:p></span></p>