Volume : 7, Issue : 5, May - 2018

CLINICO-PATHOLOGICAL STUDY OF ORAL CAVITY LESIONS-A RETROSPECTIVE ANALYSIS OF 70 CASES

Surekha Hemant Bhalekar, Sonia Kundu, Hemant Bhalekar

Abstract :

<p class="MsoNormal" style="margin-top:8.3pt;margin-right:0in;margin-bottom:8.3pt;&#10;margin-left:0in;line-height:200%"><b><i style="mso-bidi-font-style:normal"><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:#231F20">Introduction</span></i></b><b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:#231F20">: </span></b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:#231F20">Oral cavity lesions including oral cancer is a global health problem with increasing incidence and mortality rates. In India, a vast majority of oral cancers are preceded by precancerous lesions. </span><span lang="EN-IN" style="font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&quot;Times New Roman&quot;">Oral cavity shows propensity for different types of lesions at different sites. Early stages of malignant lesions canalso mimic benign lesions leading to incorrect diagnosis and treatment. Histopathology is still thegold standard in forming an accurate diagnosis of oral lesions. The present retrospective study was carried out to assess the pattern of various oral cavity lesions and to find out their clinico -pathological correlation.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%;mso-layout-grid-align:none;&#10;text-autospace:none"><b><i style="mso-bidi-font-style:normal"><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:#231F20">Aim and Objectives</span></i></b><b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:#231F20">: </span></b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:#231F20">Study was carried out to find out the types and relative frequency of the oral cavity lesions and to assess their correlation with age, sex and site distribution.<b><o:p></o:p></b></span></p> <p class="MsoNormal" style="line-height:200%;mso-layout-grid-align:none;&#10;text-autospace:none"><b><i style="mso-bidi-font-style:normal"><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Materials and Methods</span></i></b><b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">: </span></b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">It was a retrospective study carried out at </span><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:&quot;Times New Roman&quot;">the Dr Bhalekar&rsquo;s pathology lab, Panvel, Navi Mumbai,India</span><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">. A total 70 cases of oral cavity lesions were studied.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%;vertical-align:top"><b><i style="mso-bidi-font-style:normal"><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Results:</span></i></b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;&quot;Times New Roman&quot;;color:black"> Out of total 70 cases, 46 cases (65.72%) were males and 24 cases(34.28%) were females with a Male: Female ratio of 1.9: 1. Neoplastic lesions accounted for 82.8% cases comprising of 7.1% benign, 24.3% premalignant and 51.4% malignant pathology. Non-neoplastic lesions accounted for 17.2% cases.</span><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;color:black">The most common age group in oral lesions, maximum incidence of oral non neoplastic and neoplastic lesions was seen in 31 - 45 years comprising of 37.1% cases, 8.5% cases and 28.5% cases respectively. </span><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;&quot;Times New Roman&quot;;color:black">Overall lesions mostly involved the buccal mucosa (41.4%) followed bytongue(40%). Squamous cell carcinoma was seen in maximum number of cases (42.9%) followed by Leukoplakia with dysplasia (12.8%) and Erythroplakia (11.4%).<o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:8.3pt;margin-right:0in;margin-bottom:8.3pt;&#10;margin-left:0in;line-height:200%"><b><i style="mso-bidi-font-style:normal"><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Conclusion:</span></i></b><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;&quot;Times New Roman&quot;">Present study showed that majority of the oral cavity lesions were malignant thus highlighting the importance of biopsy and histopathological typing to rule out malignancy in any mass lesion of the oral cavity. </span><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">National level educational campaigns about the risk factors and early signs/symptoms associated with these diseases is the need of hour.</span><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&quot;Times New Roman&quot;"><o:p></o:p></span></p>

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Cite This Article:

Surekha Hemant Bhalekar, Sonia Kundu, Hemant Bhalekar, CLINICO-PATHOLOGICAL STUDY OF ORAL CAVITY LESIONS-A RETROSPECTIVE ANALYSIS OF 70 CASES, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-5 | May-2018


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