Volume : 7, Issue : 6, June - 2018

DEXMETOMIDINE AS ADJUVENT TO BUPIVACAINE IMPROVES POSTOPERATIVE ANALGESIA IN BRACHIAL PLEXUS BLOCKADE

Dr Ashwini Patel, Dr. Mona Bhalavi

Abstract :

<p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Background</span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">The purpose of this study was to evaluate the effect of the addition of 50microgmdexmetomedine to 20 ml of<span style="mso-spacerun:yes">&nbsp; </span>bupivacaine on postoperative analgesic effects of achial plexus block in forearm surgery.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Methods</span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">In 40 patients scheduled for<span style="mso-spacerun:yes">&nbsp; </span>forearm<span style="mso-spacerun:yes">&nbsp; </span>surgery, BPB was preoperatively performed with 20 ml of 0.5%<span style="mso-spacerun:yes">&nbsp; </span>bupivacaine under the guidance of<span style="mso-spacerun:yes">&nbsp; </span>a nerve stimulator. Patients were randomly allocated to receive the same volume of normal saline (Group I), 50microgm of dexmetomidine (Group II),. A blind observer recorded total analgesic consumption, complication, and patient satisfaction using a visual analogue <span style="mso-spacerun:yes">&nbsp;</span>scale at 0,<span style="mso-spacerun:yes">&nbsp; </span>6, 12 <span style="mso-spacerun:yes">&nbsp;</span>hours <span style="mso-spacerun:yes">&nbsp;</span>after the operation.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Results</span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">All patients had successful BPB and excellent analgesic effects less than VAS 4 up to discharge time. VAS in Group II at<span style="mso-spacerun:yes">&nbsp; </span>6 h and 12 h was statistically much lower than in Group I . There were no differences in total analgesic consumption, , complications, and patient satisfaction.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Conclusion</span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">We conclude that the addition of 50microgm of dexmetomedine to 20 ml of 0.5%<span style="mso-spacerun:yes">&nbsp; </span>bupivacaine in BPB showed improvement of postoperative analgesia for<span style="mso-spacerun:yes">&nbsp; </span>forearm<span style="mso-spacerun:yes">&nbsp; </span>operation without any specific complications.<o:p></o:p></span></p>