Volume : 7, Issue : 4, April - 2018

Antimicrobial efficacy of antimicrobial photodynamic therapy (aPDT) as an adjunct to non-surgical periodontal therapy: a randomized controlled trial

Dr. Shaswata Karmakar, Dr. Shobha Prakash

Abstract :

<p class="MsoNormal" style="text-align:justify;line-height:200%"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Background: </span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Antimicrobial photodynamic therapy (aPDT) has been introduced in periodontal therapy in an attempt to improve the efficacy of conventional root surface deidement. The aim of the present study was to microbiologically evaluate the efficacy of aPDTto non-surgical periodontal treatment in chronic periodontitis patients. <o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Methods:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> Twenty subjects with Chronic Periodontitis were randomly treated with scaling and root planning (SRP) (control) and SRP with aPDT (test). Sites of the control group and test group were treated by SRP andSRP+aPDT,respectively. Subgingival plaque samples were collected from both the sites and sent for microbiological analysis. <span style="mso-bidi-font-weight:bold">Microbial profiles from the samples were assessed at baseline and after 3 months.<o:p></o:p></span></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Results: </span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-weight:bold">Intra-group analysis after 3 months showed significant reduction in all the periopathogens inboth the groups whereas inter-group analysis showed non-significant results.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Conclusion:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-bidi-font-weight:bold">present study suggests that application of aPDTcould be a beneficial adjunct to non-surgical periodontal therapy.<o:p></o:p></span></p>