Volume : 7, Issue : 4, April - 2018
OPTIMAL ELECTROLYTE MANAGEMENT AFTER CARDIAC SURGERY: A RETROSPECTIVE OBSERVATIONAL STUDY
Dr Jyoti Prasad Kalita, Prof. Manuj Kumar Saikia, Dr Intekhab Alam
Abstract :
<p class="MsoNormal" style="margin-top:15.4pt;margin-right:0in;margin-bottom: 7.7pt;margin-left:0in;text-align:justify;text-justify:inter-ideograph; line-height:150%;mso-outline-level:3;background:white"><span style="font-size: 12.0pt;line-height:150%;font-family:"Times New Roman","serif";mso-fareast-font-family: "Times New Roman"">Introduction<b style="mso-bidi-font-weight:normal"><o:p></o:p></b></span></p> <p class="MsoNormal" style="margin-top:8.3pt;margin-right:0in;margin-bottom:8.3pt; margin-left:0in;text-align:justify;text-justify:inter-ideograph;line-height: 150%;background:white"><span style="font-size:12.0pt;line-height:150%; font-family:"Times New Roman","serif";mso-fareast-font-family:"Times New Roman"; color:black">Electrolyte imbalance after cardiac surgery is an established finding which leads to higher incidence of ventricular and supraventricular arrhythmias. Patients undergoing cardiac surgical procedures under cardiopulmonary bypass is the most important cause of electrolyte depletion. Preventing electrolyte disorders is thus an important goal of therapy in such patients. Though the measurement of levels of potassium is done regularly, other electrolytes such as magnesium, and calcium are measured far less frequently. We therefore conducted the present study to assess electrolyte levels in such patients and the optimum level of these to avoid complications.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:15.4pt;margin-right:0in;margin-bottom: 7.7pt;margin-left:0in;text-align:justify;text-justify:inter-ideograph; line-height:150%;mso-outline-level:3;background:white"><span style="font-size: 12.0pt;line-height:150%;font-family:"Times New Roman","serif";mso-fareast-font-family: "Times New Roman"">Methods<o:p></o:p></span></p> <p class="MsoBodyText" style="margin-top:.05pt;text-align:justify;text-justify: inter-ideograph;line-height:150%"><span style="font-size:12.0pt;line-height: 150%;font-family:"Times New Roman","serif";mso-fareast-font-family:"Times New Roman"; color:black">Levels of magnesium, potassium, calcium and sodium were measured in 160 consecutive patients undergoing various cardiac surgical procedures undergoing extracorporeal circulation were examined. The normal reference values for these electrolytes in our laboratory were as follows (all in mmol/l): magnesium 0.8–1.1, potassium 3.8–4.8, calcium 2.20–2.60 and sodium 135–145. The patients were divided in two groups keeping a cut of as follows (all in mmol/l): magnesium 1.0, potassium 4.0, calcium 2.5 and sodium 135<span style="mso-tab-count:1"> </span>, Group 1 has lower than the cut of mark and group 2 had higher than the cut of mark. Intravenous potassium supplementation and magnesium supplementation was received at the time of surgery.</span><span style="font-size:12.0pt;line-height:150%;font-family:"Times New Roman","serif"; mso-font-width:105%"> Serum </span><span style="font-size:12.0pt;line-height: 150%;font-family:"Times New Roman","serif";mso-fareast-font-family:"Times New Roman"; color:black">magnesium, potassium, calcium and sodium</span><span style="font-size:12.0pt;line-height:150%;font-family:"Times New Roman","serif"; mso-font-width:105%"> concentrations were determined<span style="mso-spacerun:yes"> </span>onICUadmissionand6,24 and 48 hrs <span style="letter-spacing:-.15pt">later.</span></span><span style="font-size:12.0pt; line-height:150%;font-family:"Times New Roman","serif";mso-font-width:102%"><o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:8.3pt;margin-right:0in;margin-bottom:8.3pt; margin-left:0in;text-align:justify;text-justify:inter-ideograph;line-height: 150%;background:white"><span style="font-size:12.0pt;line-height:150%; font-family:"Times New Roman","serif"">Results</span><span style="font-size: 12.0pt;line-height:150%;font-family:"Times New Roman","serif";mso-fareast-font-family: "Times New Roman";color:black"><o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:8.3pt;margin-right:0in;margin-bottom:8.3pt; margin-left:0in;text-align:justify;text-justify:inter-ideograph;line-height: 150%;background:white"><span style="font-size:12.0pt;line-height:150%; font-family:"Times New Roman","serif"">There was significant differences were found either in<span style="mso-spacerun:yes"> </span>the<span style="mso-spacerun:yes"> </span>primary<span style="mso-spacerun:yes"> </span>end<span style="mso-spacerun:yes"> </span>point<span style="mso-spacerun:yes"> </span>(hours<span style="mso-spacerun:yes"> </span>of<span style="mso-spacerun:yes"> </span>intubation) or in the secondary end points (length of inotropic support, new atrial fiillation, ventricular tachycardia or ventricular fiillation, length of intensive care unit <span style="letter-spacing:-.25pt">stay,</span> ICU or hospital mortality).</span><span style="font-size:12.0pt;line-height:150%;font-family: "Times New Roman","serif";mso-fareast-font-family:"Times New Roman";color:black"><o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:8.3pt;margin-right:0in;margin-bottom:8.3pt; margin-left:0in;text-align:justify;text-justify:inter-ideograph;line-height: 150%;background:white"><span style="font-size:12.0pt;line-height:150%; font-family:"Times New Roman","serif";mso-fareast-font-family:"Times New Roman"">Conclusion<span style="color:black"><o:p></o:p></span></span></p> <p class="MsoNormal" style="margin-top:8.3pt;margin-right:0in;margin-bottom:8.3pt; margin-left:0in;text-align:justify;text-justify:inter-ideograph;line-height: 150%;background:white"><span style="font-size:12.0pt;line-height:150%; font-family:"Times New Roman","serif";mso-fareast-font-family:"Times New Roman"; color:black">Patients undergoing cardiac surgery with extracorporeal circulation are at high risk for electrolyte depletion, despite intraoperative supplementation. The probable mechanism is a combination of increased urinary excretion and intracellular shift induced by a combination of extracorporeal circulation and decreased body temperature during surgery (hypothermia induced diuresis). Our findings may partly explain the high risk of tachyarrhythmia in patients who have undergone cardiac surgery. Prophylactic supplementation of potassium, magnesium and calcium should be seriously considered in all patients undergoing cardiac surgical procedures, should be kept at higher normal range.Levels of these electrolytes should be monitored frequently in such patients.<o:p></o:p></span></p>
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Download PDF Journal DOI : 10.15373/2249555XCite This Article:
Dr Jyoti Prasad Kalita, Prof. Manuj Kumar Saikia, Dr Intekhab Alam, OPTIMAL ELECTROLYTE MANAGEMENT AFTER CARDIAC SURGERY: A RETROSPECTIVE OBSERVATIONAL STUDY, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-4 | April-2018


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