Volume : 7, Issue : 3, March - 2018

ANTI-HYPERTENSIVE EFFECT OF Moringa oleifera lam. LEAVES DECOCTION - A PILOT STUDY

Dr. Lakshmy C Senan, Dr. Balaji S, Dr. Rabinarayan Tripathy

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;&#10;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-ascii-theme-font:&#10;minor-bidi;mso-hansi-theme-font:minor-bidi;mso-bidi-font-family:&quot;Times New Roman&quot;;&#10;mso-bidi-theme-font:minor-bidi;color:black;background:white">Hypertension is the major cause of CVDs and stroke around the globe and </span><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-ascii-theme-font:minor-bidi;mso-hansi-theme-font:minor-bidi;mso-bidi-font-family:&#10;&quot;Times New Roman&quot;;mso-bidi-theme-font:minor-bidi;color:#333333;background:white">is estimated to cause about 12.8% of </span><span style="font-size:12.0pt;&#10;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-ascii-theme-font:&#10;minor-bidi;mso-hansi-theme-font:minor-bidi;mso-bidi-font-family:&quot;Times New Roman&quot;;&#10;mso-bidi-theme-font:minor-bidi;background:white">all the<span style="color:&#10;#333333"> deaths.</span><span style="color:black"> The worldwide occurrence of hypertension has increased from 4.5%, to 7% from 2007-2010 (WHO</span>-2008; AU-2013</span><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-ascii-theme-font:minor-bidi;mso-hansi-theme-font:minor-bidi;mso-bidi-font-family:&#10;&quot;Times New Roman&quot;;mso-bidi-theme-font:minor-bidi">). Several in-vivo studies have been done in rats to prove the safety and efficacy of leaves<i> of Moringa </i>(Shigru) an Ayurvedic shrub in hypertension¹.<span style="color:black;background:white"> Safety and efficacy studies did not show any toxicity till a dose of 100&thinsp;mg/kg body weight².</span><span class="apple-converted-space"><span style="color:red;background:white">&nbsp;</span></span>This pilot study was conducted on 10 human subjects diagnosed with spontaneous hypertension. The paper was presented as a poster in the 104^th Indian Science Congress held at Tirupati, Andhra Pradesh. The study has proved that the decoction of <i style="mso-bidi-font-style:normal">Moringa oleifera</i> leaves are effective in reducing blood pressure.<span style="color:red;&#10;background:white"><o:p></o:p></span></span></p>