Volume : 6, Issue : 11, November - 2017

CHANGING CONSUMPTION PATTERN OF RURAL PEOPLE IN THE LINES OF NEW ECONOMIC POLICY IN INDIA

Mrs. V. Kanimozhi, Dr. N. Kannan

Abstract :

<p>&nbsp;<span style="font-family: &quot;Times New Roman&quot;, serif; text-align: justify;">Refractory celiac disease (RCD) is defined as a clinical complicated variant of celiac disease (CD), characterized by the persistence of recurrent malabsorption symptoms and villous atrophy, despite a strict adherence to a gluten-free diet (GFD) for at least 6-12 months, in the absence of other causes of non-response and overt associated any type of cancer. </span><span style="font-family: &quot;Times New Roman&quot;, serif; text-align: justify;">&nbsp;</span><span style="font-family: &quot;Times New Roman&quot;, serif; text-align: justify;">The prognosis is dismal and fortunately its prevalence is very rare, being estimated, in less than 5% of CD diagnosed total population.</span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:150%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-ansi-language:EN-US">We describe the onset of this complication in the same family, affecting two&nbsp; siblings, a man of 59 years with a progressive myoclonic ataxia and a woman of 50 years,&nbsp; with an jejunal localization of an enteropathy-associated T-cell lymploma &nbsp;(EATL). Both died within a few months after the onset of their RCD, as a consequence of the associated complications of the illness.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:150%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-ansi-language:EN-US">For establishing a firm diagnosis it is necessary to confirm the presence of abnormal changes in the intraepithelial lymphocyte population. These patients did not express the surface receptors (CD3 and CD8) and had a positive monoclonal detection of T receptor chains confirmed in both siblings, as positive markers of immunological diagnosis of RCD-2 type in these patients, according to an aggressive clinical course and a poor prognosis.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:150%"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-ansi-language:EN-US">The family association of this important complication (RCD-type II) is remarkable and the neurologic complication of a myoclonic ataxia is very uncommon.<o:p></o:p></span></p>