Volume : 6, Issue : 7, July - 2017

A case of clinically significant Anti-M antibody

Dr. Kaushik R. Prajapati, Dr. Parul D. Bhansali, Dr. Harsha R. Gajjar, Dr. Zenny H. Chavda

Abstract :

<p>&nbsp;<i><span lang="EN-IN" style="font-size:14.0pt;mso-bidi-font-size:11.0pt;line-height:115%;&#10;font-family:&quot;Calii&quot;,sans-serif;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:&#10;&quot;Times New Roman&quot;;mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:&#10;minor-latin;mso-bidi-font-family:&quot;Times New Roman&quot;;mso-bidi-theme-font:minor-bidi;&#10;mso-ansi-language:EN-IN;mso-fareast-language:EN-IN;mso-bidi-language:AR-SA">The MNS antigen system is a human blood group system based upon two genes; glycophorin A and glycophorin B, located on chromosome number 4. There are currently 46 antigen in the system, but the&nbsp; five most important antigens are M,N,S,s and U. Most anti -M antibodies are naturally occurring IgM antibodies. Anti-M reacting at room temperature can be a cause of blood group discrepancy. Antibodies to Anti-M antigen are associated with hemolytic transfusion reaction if antigen reacting incompatible pack cells given</span></i></p>