Volume : 8, Issue : 11, November - 2019

PRIMARY COLD AGGLUTININ DISEASE IN ADOLESCENT AGE - A RARE PRESENTATION

Dr. V. C. Singel, Dr. Jitendra H. Parikh, Dr. Swansu Batra, Dr. Sangita Malaviya, Dr. Krunal Patel

Abstract :

Cold agglutinin disease is a rare form of autoimmune hemolytic anemia caused by cold reacting autoantibodies directing against the RBC memane antigens . Majority of cases of Cold agglutinin disease are secondary to infections , autoimmune diseases and Lymphoproliferative disorders . Primary cold agglutinin disease is extremely rare with estimated Incidence of 1 per million and prevalence of 16 per million with the mean age of presentation being 67 years . A high index of suspicion and meticulous work up is required for diagnosis of primary cold agglutinin disease . Hereby , we aim to discuss a case of Primary cold agglutinin disease presented at adolescent age and it’s management