Volume : 8, Issue : 3, March - 2019

CORRELATION BETWEEN IRON STORAGE AND THYROID PROFILE IN HYPOTHYROIDISM: A CROSS- SECTIONAL STUDY

Tanima Mandal, Sumanta Banerjee, Subhayan Lahiri

Abstract :

The enzymatic activity of heme containing Thyroperoxidase, necessary for thyroid hormone production, is hampered in iron depleted states. Keeping that in mind, a cross-sectional tertiary care hospital based study was conducted at B.S. Medical College and Hospital, in Bankura with 62 hypothyroid participants and same number of age and sex matched controls. In that study, it was found that hypothyroidism was strongly and significantly associated with iron deficient state of body. It was also found that 48% of hypothyroid patients had low iron storage (ferritin < 25 ng/mL) when thyroid stimulating hormone (TSH) is more than 10 mIU/L. Ferritin level was found to be significantly lower in cases with respect to controls.