Volume : 8, Issue : 3, March - 2019

SERUM hsCRP AS A PREDICTOR OF CARDIO VASCULAR DISEASE IN CHRONIC KIDNEY DISEASE

Dr. M. Naiyna Mohamed, Dr. S. Syed Ali Fathima

Abstract :

Background: CKD is a global public health problem along with serious complications like ESRD, CVD and Premature Death. Serum hs-CRP is a strong predictor of cardiovascular mortality in CKD patients. Hence in this study hsCRP was estimated in patients with different stages of CKD and the relationship between serum hsCRP and estimated GFR was analyzed. Aim: To estimate serum hsCRP in patients with CKD and to compare them with healthy controls. Results: In this study we observed a significantly higher levels of hsCRP in cases when compared to controls [mean value: cases 4.5432 ± 2.9689; controls 0.5360 ± 0.2343, Pvalue < 0.05].As the renal function declined, we observed a progressive increase in the serum hsCRP levels. Conclusion. Life style modification and therapeutic intervention should be taken as soon as a diagnosis of CKD is made to reduce the cardiovascular risk