Volume : 8, Issue : 3, March - 2019

Comparison Between Clonidine And Dexmedetomidine As Adjuvant For Supraclavicular Brachial Plexus Block

Dr. Kaushik Dutta, Dr. Rita Haldar Dasgupta , Dr. Anurup Pakhira, Dr. Debasish Bhar

Abstract :

Objectives: 1) To compare the efficacy of two alpha2 agonist drugs, namely clonidine and dexmedetomidine when added to levobupivacaine as adjuvant for achial plexus block for upper limb surgery. We compared the onset and duration of sensory and motor blockade, duration of analgesia, and haemodynamic changes. 2) To study the occurrence of any adverse effect in perioperative period. Methodology: 140 patients of ASA Class I and II, aged 18-60 years, scheduled for upper limb surgery were studied in a prospective randomized double-blind manner. Supraclavicular achial plexus block was administered to patients who were randomly divided into two groups – Group A and Group B. For achial plexus block, Group A received 0.25% levobupivacaine, 0.5ml / Kg, along with clonidine 2mcg/ml. Group B received 0.25% levobupivacaine, 0.5ml / Kg, along with dexmedetomidine 2mcg/ml. Results: The time of onset of sensory and motor blocks in Group B (dexmedetomidine group) were quicker than that of Group A (clonidine group). Prolongation of sensory and motor blocks and mean duration of analgesia were observed in Group B compared to Group A. Conclusion: Dexmedetomidine is found to be superior adjuvant than clonidine when used with levobupivacaine for achial plexus block.